Immunology – Adaptive Immunity (B cell Activation, Hypermutation and Class Switching Overview)
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Thanq sir
It's my first year on medical school, and I have my finals in microscopic anatomy on next friday! I have sacrificed so much to learn everything. Its new year in 3 days, but I have cancelled all my plans.. None of my friends understand why I study so hard, and I don't blame them. Only medical students understand the struggle. I can't wait to see what the future will bring!
Thanks for the video!
life saver
Really good video, nothing is this good!!!
Lol. At 5:15 he went "now let's look at (…) in a bit more detail" after which he just explained the exact same thing again.
Don't get me wrong; I like the video. Probs and thanks to Armando Hasudungan for making it and all. I just found this detail a bit odd 🙂
Thanks for your video !! This is really really helpful !!
thank you so much for this one.
The specificity DOESN"T change by hypermutation according to my lecturer but only affinity and ig class do change its a great video though
Hi guys, I just wanna share how I've learned immunology and offer my scripts if anyone here finds it interesting. I've used mnemonics or MEMORY TECHNIQUES. What I basically did was imagining molecules as people I know and processes/pathways/principles as those people interacting in various crazy ways. And at the same time putting them in ''memory palaces'' = actual places like my or people's houses. I did it for WHOLE immunology, following Roitt's book!
It was the first time that I've tried learning that way. And it was amazing and FUN and helpful and for the first time in 4 years of college I felt like was UNDERSTANDING SOMETHING ON A DEEPER LEVEL… That was 6 months ago. And all this time I felt the need to share it somehow (video form or podcast) 'cause I really think it could be helpful to some. But there's just this fear that's stopping me… So, yeah, if, reading this, at any moment you've felt it would be interesting/useful for you to see what I've written, comment or send me a message and I'd be glad to send it to you right away. Be open minded! 🙂
Or I'd love to hear what you generally think about the idea. 🙂
Can u plz upload b cell receptors and b cell subsets
I think this lecture is too fast. You should slow down a little. 🙂 But nice work!
Maaaaan, this was so cool, you don't have idea of how much It actually helped me to understand a big part of my immunology semester. Saved my career and my scholarship. Thanx a lot, keep doing cool shit !
The antigen presented by the T-helper cell ? Do T-helpers present antigens? @4:07
Thank you
I'm studying for my graduate immunology course and your videos have been a life line. Please realize how much these videos help students learn and understand material instead of just memorization.
hi your videos are really good and helpful i have a small doubt can you please tell me whats then use of lymphocytes when macrophages and dentritic cells have already digested the antigen why does it projects on the mhc class 1
thank you
thanks
hi can anyone please help me, give me any links or even email me anything or give me a name of a book that i can read to know more about class switching?
is it not … that RSS means recombinant signal sequence and not recombinant segment sequence?
This is pure gold! Thanks a lot!
Very informative and simplified!
hey can you explain about affinity maturation?
please can give me a summary about production of B lymphocyte please quickly
Colony expansion?
thank you "."
does t lymphocytes drain from lymph to lymph nodes or they're already there waiting for antigen found on antigen presenting cells ?
thank you so much! You have helped me alot.
Thankyou so much Armando, this really allows me to visualise the concepts.
Cheers from Australia 🙂 — Keep up the great work!
Great job on this one man! Really helpful 🙂
thank you very much
I have a question about the CD4+ cells. At about the 3:30 mark you say that the Helper T cell presents the antigen to the mature B cell in the first place. I don't understand how this mechanism works considering Helper T cells don't express MHC II, but instead REACT to it. So if Helper T cells don't express MHC II how are they able to present an antigen? I thought all antigen presenting cells express MHC II. Any clarification would be great ty
thank you so much
ok but you don't explain what hypermutation does to the immunoglobulin and DNA it derives from and what class switching consists of for the same matter… jesus
hmm u are just the best!!!!!!!