Immunology – Adaptive Immunity (B cell Activation, Hypermutation and Class Switching Overview)


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35 thoughts on “Immunology – Adaptive Immunity (B cell Activation, Hypermutation and Class Switching Overview)

  1. It's my first year on medical school, and I have my finals in microscopic anatomy on next friday! I have sacrificed so much to learn everything. Its new year in 3 days, but I have cancelled all my plans.. None of my friends understand why I study so hard, and I don't blame them. Only medical students understand the struggle. I can't wait to see what the future will bring!
    Thanks for the video!

  2. Lol. At 5:15 he went "now let's look at (…) in a bit more detail" after which he just explained the exact same thing again.
    Don't get me wrong; I like the video. Probs and thanks to Armando Hasudungan for making it and all. I just found this detail a bit odd 🙂

  3. Hi guys, I just wanna share how I've learned immunology and offer my scripts if anyone here finds it interesting. I've used mnemonics or MEMORY TECHNIQUES. What I basically did was imagining molecules as people I know and processes/pathways/principles as those people interacting in various crazy ways. And at the same time putting them in ''memory palaces'' = actual places like my or people's houses. I did it for WHOLE immunology, following Roitt's book!

    It was the first time that I've tried learning that way. And it was amazing and FUN and helpful and for the first time in 4 years of college I felt like was UNDERSTANDING SOMETHING ON A DEEPER LEVEL… That was 6 months ago. And all this time I felt the need to share it somehow (video form or podcast) 'cause I really think it could be helpful to some. But there's just this fear that's stopping me… So, yeah, if, reading this, at any moment you've felt it would be interesting/useful for you to see what I've written, comment or send me a message and I'd be glad to send it to you right away. Be open minded! 🙂

    Or I'd love to hear what you generally think about the idea. 🙂

  4. Maaaaan, this was so cool, you don't have idea of how much It actually helped me to understand a big part of my immunology semester. Saved my career and my scholarship. Thanx a lot, keep doing cool shit !

  5. I'm studying for my graduate immunology course and your videos have been a life line. Please realize how much these videos help students learn and understand material instead of just memorization.

  6. hi your videos are really good and helpful i have a small doubt can you please tell me whats then use of lymphocytes when macrophages and dentritic cells have already digested the antigen why does it projects on the mhc class 1

  7. I have a question about the CD4+ cells. At about the 3:30 mark you say that the Helper T cell presents the antigen to the mature B cell in the first place. I don't understand how this mechanism works considering Helper T cells don't express MHC II, but instead REACT to it. So if Helper T cells don't express MHC II how are they able to present an antigen? I thought all antigen presenting cells express MHC II. Any clarification would be great ty

  8. ok but you don't explain what hypermutation does to the immunoglobulin and DNA it derives from and what class switching consists of for the same matter… jesus

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